Tuesday, December 31, 2019

Benefits Of Owning The Corporation Essay - 786 Words

According to Longenecker, Petty, Palich, and Hoy (2014), â€Å"an entrepreneur is a person who relentlessly pursues an opportunity, in either a new or an existing enterprise, to create value while assuming both the risk and the reward for her or his efforts† (p, 6). In other words, entrepreneurs are risk takers that are motived by profits, achievements, or success. This motivation helped Chairman Michael German (i.e., German) help grow his family business from startup to a forty-six employee company. Although German shared how the organization has successfully grown over the years, there are advantages and disadvantages of owning the corporation; therefore, his recommendations are important for future entrepreneurs. Founded by German and his son Alex German (i.e., CEO) in May 2004, German Son, Inc. (G S) is a New York based, family-owned, third party logistics provider. A brief interview with German was conducted on December 16, 2016. As per German, he decided to start the business with his son because â€Å"Alex had the expertise in the industry† while he had the business experience (M. German, personal communication, December 16, 2016). German obtained most of his business experience in the telecommunications industry. On the other hand, Alex obtained most of his experience and working relationships in the distribution industry. At the end of 2003, Alex’s employer relocated and paid him severance that equaled to his one year’s salary. As a result, Alex made theShow MoreRelatedEssay about Lockheed Martin Stakeholder Analysis1328 Words   |  6 Pageson stakeholders. Corporations have impacts on a variety of people ranging from shareholders, to governments, to ordin ary citizens. This paper analyzes the impact Lockheed Martin has on all stakeholders, both positive and negative. | Matthew Vogt Business, Government and Society 26 April 2010 Lockheed Martin: Stakeholder Analysis What is a stakeholder? A stakeholder is someone who someone who benefits or is burdened by a corporation, or someone who the corporation benefits or is burdened byRead MoreEquity Ownership Of A Company881 Words   |  4 Pages After exploring debt ownership last week, this week we are going to explore equity ownership. One of the major concerns of owning equity in a company is the ability of that company to perform, which is the only one of the only ways an investor can receive a return on an equity instrument. The most common form of equity ownership in a company is common stock and by owning shares, you are a part-owner of the company. Along with ownership comes the right to vote on certain company issues such asRead MoreDifferent Types Of Business Ownership1277 Words   |  6 Pagesstructure your business, you#39;ll need to know what your options are. The below are your choices when it comes to running your business: sole proprietorship, partnership, limited partnership, limited liability company (LLC), corporation (for-profit), nonprofit corporation, and cooperative. It is important that you choose the right structure for your business as the type of structure you choose will affect how your business is organized, taxed, and handled. Sole Proprietorship A sole proprietorshipRead MoreAcc/561 Cvp and Break-Even Analysis1552 Words   |  7 Pages000. The following items are included in the start-up fee: 1. Franchise Fee 2. Grand Opening Marketing 3. Leasehold Improvements 4. Utility and Rent Deposits 5. Training Many people dream of owning a business as opposed to working for another business. The benefits of owning a franchise is priceless if ran properly. This paper will show an estimate amount of variable costs and monthly sales in members and dollars for Snap Fitness. Also included are five examples of variable costsRead MorePolitical Economy And Democracy Essay1709 Words   |  7 Pages Corporations are the best example of capitalism in action. The main objective of a business or corporation is to ultimately make a profit, which then can be used to make investments which leads to even more profits. Essentially, the private owners in charge determine the future of that company and everyone who works there. Today, with the majority of the globe running under these mighty corporations, a sense of classism amongst the populace evolvesRead MoreBenefits Of A Partnership Is The Trust Factor1604 Words   |  7 Pagesaccordance to the law, then a partnership would be a great option for them. Corporation A corporation is the most commonly known business classification in the world today. All the major companies, such as McDonald’s and Walmart, are prime examples of a corporation. Corporations are seen as separate legal entities by the government and are therefore taxed separately, twice during the year. The actual owners of the corporation are the shareholders that have invested into it and own stock in the companyRead MoreEssay Entrepreneurship1567 Words   |  7 PagesDescribe the term Entrepreneurship and the challenges of starting a small business Entrepreneurship is the dream of a lifetime for most individuals. The idea of being in control on ones financial future by establishing, owning, and operating their own business has driven most individuals in the direction of Sole Proprietorships. Most plunge in looking at the advantage and over looking the disadvantage and challenges of Sole Proprietorships. This first challenge that one might face on the roadRead MoreCase Study : Legal Issues And Wal Mart1573 Words   |  7 Pagesvery hard for smaller businesses to compete or stay up with Wal-Mart. To add to the equation, Wal-Mart’s operation is successful due to their stakeholders, which include their employees and their customers. Focusing on the employee aspect, the corporation is assumed to be lacking in corporate social duties and responsibilities when it comes to labor efforts, which go into the reason behind the company’s success. â€Å"Wal-Mart reported a net income of over $11 billion last year—surely plenty of moneyRead MoreTypes Of Corporate Social Responsibility1539 Words   |  7 PagesOwning a business used to mean that a when company provided a good or service to a consumer it received a profit in return. Owning a business has developed into a greater thing then the cut and dry definition previously mentioned. Society’s desires have changed with the times, and it burdens businesses to accept more social responsibility for the cost of doing business. In order for a business to continue to be successful in this rapidly changing b usiness world it must accept the changes of corporateRead MoreComparison and Contrast943 Words   |  4 Pagesconvenient when handling everyday errands. Owning a gas operated transportation can benefit a parent, student or business person in prioritizing there lifestyle. However, the economy is on the rise demanding more money in fuel and oil cost. The price of gas could overwhelm any individual in today’s economy. Gas powered cars like Cadillac’s, Lincoln’s, and Buick’s could break your pockets. Fuel efficient vehicles such as the Prius, Honda insight and Chevy volt could benefit your budget as well as providing

Monday, December 23, 2019

Effective Transitions Of A Self Contained Classroom Essay

Effective Transitions in a Self Contained Classroom Julie Harrell Thomas University Table of Contents Abstract 4 Introduction 5 Review of the Literature 6 The Effect of Instructional Time 7 Classroom Management 8 Classroom Arrangement 9 Positive Behavior in the Classroom 10 Teaching Transition Strategies 11 Planned Lesson Activities and Visuals 14 Procedures/Methodology 15 Participants 15 Instruments 15 Treatment 16 Procedures 17 Data Analysis 18 Results 18 Conclusion 18 Final Comments 18 References 19 Appendices 21 Appendices A 21 Appendices B 22 Appendices C 23 Appendices D 24 Appendices E 25 Abstract Efficient transition strategies throughout the day can improve a teacher s instructional time or it can decrease it. Transitions are among the most riskiest times of the day. The busy movement, the close interaction, the loud voices and sense of freedom children have during this time, all come together to increase the possibility of misbehavior. Transitions can also waste precious learning time, bring tension and excitability to the classroom, and make it difficult to settle students back into a state of attentiveness. Therefore, this study examines the following question: 1. How does instructional time improve through the teaching of transition expectations in a first grade classroom? The purpose of this action research is to explore the most efficient transition strategies in terms of time, readiness, classroom management, and studentShow MoreRelatedThe Influence Of Departmentalization On Elementary School Students1316 Words   |  6 Pagesand misrepresentations make choices difficult, and force many school districts to create their own definitions of terms. The failure to establish static definitions continues to complicate the debate. Those that support the benefits of the self- contained classroom cite optimized individualization, time flexibility, and coordination across content areas. The advocates of departmentalization focus on the need for the teachers specialized knowledge, for increased student engagement and content masteryRead MoreThe Influence Of Departmentalization On Elementary School Students1331 Words   |  6 Pagesbenefits of the self- contained classroom site optimized individualization, time flexibility, and coordination across content are as. The advocates of departmentalization focus on the need for the teachers specialized knowledge for increased student engagement and content mastery. They claim it is unrealistic to expect elementary teachers to have the specialized knowledge that is required to facilitate instruction. Research indicates that departmentalized instruction helps students transition to the middle-schoolRead MoreTransition from Elementary to Middle School Essay1213 Words   |  5 PagesChildren confront many transitions throughout their lifetime that can be stressful. They face their first transition from home to school, elementary to middle school, middle to high school, and high school to college or work (Schumacher, 1998). However, the transition from elementary to middle school seems to be harder for adolescents due to the personal changes of puberty. Research suggests that roles, expectations, and responsibilities are the primary concerns of students (Akos, 2002). In orderRead MoreThe Importance Of A Teacher Student Relationship778 Words   |  4 Pagesunderstanding of its impact on their classroom climate and to encourage methods of class community building. The problem, therefore, is twofold - what is the impact of Exceptional Student Education (ESE) students on teacher-student relationships and what preconceived notions do teachers have that impact their relationships with their students. This is important to the field of education as we transition from the old model of secluding ESE students in self-contained classrooms to the newer model of inclusionRead MoreMy Identification Of Instructional Strategies1643 Words   |  7 PagesEven as a future teacher with limited experience teaching in a self-contained classroom, I have notions of what a positive and engaging classroom environment feels like, both from a student and an adult perspective. Sadly, reading through the vignette of Ms. T’s classroom, I did not perceive any semblance of that feeling. In fact, the classroom scenario related closely to some of the ineffective practices outlined in the works of Allington (1983), Smith (2012), Rosenblatt (1982). As well LaminackR ead MoreMajor Trends in 21st Century in Esl1029 Words   |  5 Pagesthroughout the world. Though this area is one of our greatest priorities, it is also one of our greatest challenges. The classroom environment has changed from many years ago. Teachers face the challenges of a large population who do not speak English and have high transient rates. For this large population, becoming proficient in a new language is a very difficult transition. This process can be frustrating and sometimes painful. Students learning a new language need as much language support asRead MoreThe Need to Belong: Rediscovering Maslows Hierarchy of Needs.6034 Words   |  25 PagesThe Need to Belong: Rediscovering Maslows Hierarchy of Needs. by: Norman Kunc Axis Consultation and Training Ltd Originally published in: Villa, R., Thousand, J., Stainback, W. Stainback, S. Restructuring for Caring Effective Education. Baltimore: Paul Brookes, 1992.  © Copyright 1992 Paul H. Brookes Publishers. Newtonian principles of physics were regarded as true until Einstein demonstrated that they provided an inadequate explanation of the laws of nature. Similarly, Freudian analysts viewedRead MoreEssay about Emotional, Behavioral, and Physical Disabilities2451 Words   |  10 Pagesdifferent skills throughout their life. This paper will explain and describe effective teaching strategies for exceptional students. And give examples of these strategies, for students with behavioral and emotional disorders, physical, and health impairments and also those who have traumatic brain injury. It will also show ways of helping these students learn to advocate for themselves with confidence and enhance their self esteem. Teaching Strategies Emotional and Behavior Disorders Some studentsRead MoreAdhd And Its Effects On Children Essay1588 Words   |  7 Pagesable to function appropriately in a typical classroom environment.   For this population of students, school and life satisfaction severely decreases.   Art jewelry as a form of therapy may allow students to decrease or ease the need for ADHD medication, and increase students’ abilities to maintain focus and complete tasks.   Ã‚     Ã‚  Ã‚   One personal account I can recall is about   a boy in my classroom who just can’t stay seated; he often walks around the classroom and distract other students; making noiseRead MoreDiversity Is A Scary Thing2144 Words   |  9 Pagesoften between these peers. There are many different viewpoints on the best way to facilitate the growth of these relationships, but with enough research the correct answer is transparently clear. Although some would argue that full inclusion or self contained classes for children with special educational needs is the best way to enrich the learning environment for all students, individualized inclusion is the only alternative that positions classes in a way that significantly improves the social and

Sunday, December 15, 2019

An Outline of the Cell Theory Free Essays

string(162) " introduced to humans to replace the damaged bone marrow of some leukemia patients †¢Bone marrow transplants are one of the many therapeutic uses of stem cells\." Chapter 2 IB Biology 2. 1 Cell Theory 2. 1. We will write a custom essay sample on An Outline of the Cell Theory or any similar topic only for you Order Now 1 Outline the cell theory (2). †¢All organisms are composed of one or more cells †¢Cells are the smallest units of life †¢All cells come from preexisting cells †¢TOK: cell theory replaces the former ideas of spontaneous generation or abiogenesis in which inanimate matter assembles itself into living forms †¢Exception: muscle cells- more than 1 nucleus, very long; (fungal cells) hyphae roots- not a single unit; protoctista- not specialized to single function; subcellular things like organelles 2. 1. Discuss the evidence for the cell theory (3). †¢Robert Hooke first described cells in 1665 while observing cork with a microscope he built. Coined the term â€Å"cell† Antoine van Leeuwenhoek observed the 1st living cells and referred to them as animalcules. â€Å"microscope† †¢In 1838, botanist Mathias Schleiden stated that plants are made of independent separate being called cells. Later, Theoder Schwann made a similar statement about animals. †¢The 2nd principle continues to gain support because we have not been able to find any living entity that is not made of at least one cell. Louis Pasteur in the 1860s performed experiments to support the last principle. After sterilizing chicken broth by boiling, Pasteur showed that living organisms would not ‘spontaneously’ reappear. â€Å"biogenesis† †¢Only after exposure to preexisting cells was life able to re-establish itself in the chicken broth. †¢Eukaryotes- mitosis; prokaryotes- binary fission; thus all cells have a common ancestor- original ancestral form 2. 1. 3 State that unicellular organisms carry out all the functions of life (1). †¢Functions include: Metabolism- chemical reactions that occur within an organism †¢Growth- may be limited but is always evident in some way †¢Reproduction- hereditary molecules that can be passed to offspring †¢Response- to environment is imperative to survival †¢Homeostasis- maintain a constant internal environment ex: temp †¢Nutrition- provide a source of compounds with many chemical bonds which can be broken to provide the organism with the NRG and the nutrients necessary to maintain life CHNOPS 2. 1. 4 Compare the relative sizes of molecules, cell membrane thickness, viruses, bacteria, organelles and cells, using the appropriate SI unit (3). Cells- 100 micrometers (plant) †¢Organelles- lt; 10 micrometers †¢Bacteria- 1 micrometer †¢Viruses- 100 nanometers †¢Membranes- 10 nanometers thick †¢Molecules- 1 nanometer †¢Animal cell- 10 micrometers †¢cm = 10-2 m †¢mm = 10-3 m †¢um = 10-6 m †¢nm = 10-9 m †¢A = 10-10 m 2. 1. 5 Calculate the linear magnification of drawings and the actual size of specimens in images of known magnification (2). †¢Magnification = size of image divided by the size of specimen †¢Magnification = measured length / scale bar level †¢Actual size = measured length / magnification 2. 1. Explain the importance of the surface area to volume ratio as a factor limiting cell size (3). †¢In the cell, the rate of heat and waste production and rate of resource consumption are functions that depend of its volume. †¢Most of the chemical reactions occur in the interior of the cell and its size affects the rate of these reactions. †¢The surface of the cell, the membrane, controls what materials move in and out of the cell. †¢Cells with more surface are per unit volume are able to move materials in and out of the cell, for each unit volume of the cell. As the width of the object increases, the surface area also increases but at a much slower rate than the volume. †¢This means that a large cell has less surface area to bring in needed materials and to rid the cell of waste than a small cell. †¢Because of this, cells are limited to the size they can attain and still be able to carry out the functions of life. Large animals have more cells not larger ones. †¢A large surface area to volume ratio means the cell can act more efficiently: for every unit of volume that requires nutrients or produces waste, there is more membrane to serve it. But this is not always an advantage- cell can lose heat quickly. †¢As organisms grow, cells divide. 2 small cells are more efficient than one. †¢Alveoli in lungs maximize surface for gas exchange. 2. 1. 7 State that multicellular organisms show emergent properties (1). †¢Different things come together to make process †¢Cells-tissues-organs-etc. †¢Ability to reproduce themselves. Allows possibility of growth and for replacement of damaged or dead cells. 2. 1. 8 Explain that cells in multicellular organisms differentiate to carry out specialized functions by expressing some of their genes but not others (3). Start out as single cell that reproduces at a rapid rate then the resulting cells go through a differentiation (different cells- different functions- to run an organism) process to produce all required cell types that are necessary for organism. †¢Every cell in a multicellular organism contains all the genes of that organism. However, the genes that are activated vary from cell to cell. †¢Differentiation- when we break something complex into its component pieces, they each appear to be simple. Combined, they can perform a whole new function. Cells within a multi cellular organism specialize their function. †¢Examples: muscles cells, cardiac cells †¢This differentiation process is the result of the expression of certain specific genes but not others †¢Genes allow for the production of all different cells in the organism †¢Each cell contains all the genetic info for the production of the complete organism †¢Each cell becomes a specific type of cell dependent of which DNA segment becomes active 2. 1. 9 State that stem cells retain the capacity to divide and have the ability to differentiate along different pathways (1). Retain ability to divide and differentiate into various cell types †¢Embryonic stem cells retain the ability to form any type of cell in an organism and can even form a complete organism †¢When stem cells divide to form a specific type of tissue, they also produce some cells that remain as stem cells. This allows for the continual production of a particular type of tissue. †¢Pluripotent- give rise to any type of cell †¢Treating diseases? 2. 1. 10 Outline one therapeutic use of stem cells (2). †¢Replace differentiated cells lost due to injury Therapeutic cloning- implanted stem cells replace lost cells †¢Tissue- specific stem cells- these cells reside in certain tissue types and can only produce new cells of that particular tissue †¢For example, stem cells have been introduced to humans to replace the damaged bone marrow of some leukemia patients †¢Bone marrow transplants are one of the many therapeutic uses of stem cells. You read "An Outline of the Cell Theory" in category "Papers" Stem cells found in the bone marrow give rise to the red blood cells, white blood cells and platelets in the body. These stem cells can be used in bone marrow transplants to treat people who have certain types of cancer. When a patient has cancer and is given high doses of chemotherapy, the chemotherapy kills the cancer cells but also the normal cells in the bone marrow. This means that the patient cannot produce blood cells. So before the patient is treated with chemotherapy, he or she can undergo a bone marrow harvest in which stem cells are removed from the bone marrow by using a needle which is inserted into the pelvis (hip bone). Alternatively, if stem cells cannot be used from the patient then they can be harvested from a matching donor. After the chemotherapy treatment the patient will have a bone marrow transplant in which the stem cells are transplanted back into the patient through a drip, usually via a vein in the chest or the arm. These transplanted stem cells will then find their way back to the bone marrow and start to produce healthy blood cells in the patient. Therefore the therapeutic use of stem cells in bone marrow transplants is very important as it allows some patients with cancer to undergo high chemotherapy treatment. Without this therapeutic use of stem cells, patients would only be able to take low doses of chemotherapy which could lower their chances of curing the disease. †¢Ethical issues- embryonic stem cells come from embryos obtained from labs doing IVF. involves death of embryo. 2. 2 Prokaryotic Cells 2. 2. 1 Draw and label a diagram of the ultrastructure of Escherichia coli (E. coli) as an example of a prokaryote (1). †¢Plasmid is circular thing not on diagram. Refer to book. †¢Size of cell: 1-2 um †¢Absence of membrane bound organelles Prokaryote examples: (look at notes for pictures) †¢straight rod- Escherichia †¢Club shaped rod- corynebacterium †¢Spore forming rods- bacillus †¢Coccus Staphylococcus 2. 2. 2 Annotate the diagram with the functions of each named structure. †¢Cell wall: Protects the cell from the outside environment and maintains the shape of the cell. It also prevents the cell from bursting if internal pressure rises. †¢P lasma membrane: Semi-permeable membrane that controls the substances moving into and out of the cell. It contains integral and peripheral proteins. Substances pass through by either active or passive transport. †¢Cytoplasm: Contains many enzymes used to catalyze chemical reactions of metabolism and it also contains the DNA in a region called the nucleoid. Ribosomes are also found in the cytoplasm. †¢Pili: Help bacteria adhere to each other for the exchange of genetic material. Involved in transfer of DNA in a process called conjugation (direct contact between bacterial cells in which plasma DNA is transferred between a donor and a recipient cell) †¢Flagella (singular flagellum): Made of a protein called flagellin. Helps bacteria move around (mobility) †¢Ribosomes: They are the site of protein synthesis. Contributes to protein synthesis by translating messenger RNA. free in cytoplasm (70s) †¢Nucleoid: Region containing DNA; involved with cell control and reproduction †¢Plasmid- small, circular DNA not connected to main chromosome; replicate independently of chromosomal DNA; not required by cell under normal conditions but it may help the cell adapt to unusual circumstances; normal to find at least one anti-biotic resistance gene within a plasmid †¢Slime capsule- sticky layer outside of cell wall, sticks cells together . 2. 3 Identify structures from 2. 2. 1 in electron micrographs of liver cells (2). 2. 2. 4 State that prokaryotic cells divide by binary fission (1). †¢Binary fission- simple division process in which DNA is copied and 2 daughter chromosomes become attached to different regions on plasma membrane and cell divides into 2 genetically identical daughter cell s. Process elongation of cell 2. 3 Eukaryotic Cells 2. 3. 1 Draw and label a diagram of the ultrastructure of a liver cell as an example of an animal cell (1). . 3. 2 Annotate the diagram with the functions of each named structure. †¢Ribosomes: Found either floating free in the cytoplasm or attached to the surface of the rough endoplasmic reticulum and in mitochondria and chloroplast. Ribosomes are the site of protein synthesis as they translate messenger RNA to produce proteins. †¢Rough endoplasmic reticulum: Can modify proteins to alter their function and/or destination. Synthesizes proteins to be excreted from the cell. Lysosome: catalyze the breakdown of proteins, nucleic acids, lipids and carbs, fuse with old or damaged organelles so recycling can occur, breakdown of materials that are brought in by phagocytosis †¢Golgi apparatus: Receives proteins from the rough endoplasmic reticulum and may further modify them. It also packages proteins before the protein is sent to it’s final destination which may be intracellu lar or extracellular. †¢Mitochondrion: Is responsible for aerobic respiration. Converts chemical energy into ATP using oxygen. †¢Nucleus: Contains the chromosomes and therefore the hereditary material. It is responsible for controlling the cell. Extra: †¢Smooth ER- production of membrane phospholipids can cellular lipids, production of sex hormones, detoxification of drugs in liver, storage of calcium ions needed for muscle contractions, transportation of lipid based compound, to aid in liver in releasing glucose into bloodstream when needed †¢Centrosome- a pair of centrioles at right angles; involved in assembling microtubules which are important in providing structure and allowing movement and cell division †¢Vacuole- storage organelle; store potential food to provide nutrition, metabolic wastes and toxins to be expelled, and ater; enables cells to have a higher surface area to volume ratios even at larger sizes; in plants, uptake of h2o provides rigidity 2. 3. 3 Identify structures from 2. 3. 1 in electron micrographs of liver cells (2). 2. 3. 4 Compare prokaryotic and eukaryotic cells (3). Prokaryote Eukaryote DNA in a ring form without proteinDNA with proteins a s chromosomes/chromatin DNA free in the cytoplasm- no nucleusDNA enclosed within a nuclear envelope No mitochondriamitochondria 70S ribosomes80S ribosomes No internal compartmentalization to form organellesinternal compartmentalization present to form many types of organelles Size less than 10 micrometersSize more than 10 micrometers †¢also: unicellular vs. multicellular †¢no membrane bound organelles vs. membrane bound organelles †¢binary fission vs. mitosis †¢asexual reproduction vs. asexual and sexual reproduction †¢similarities: both cells have some sort of outside boundary that always involves a plasma membrane, both carry out all functions of life, DNA is present in both . 3. 5 State 3 differences between plant and animal cells (1). Plant Animal Outer cell wall with a plasma membrane just insideOnly a plasma membrane Chloroplasts No chloroplasts Large centrally located vacuolesNo vacuoles/ or small ones Store carbs as starchStore carbs as glycogen Do not contain centrioles within a centrosome areaContain centrioles within a centrosome area Fixed, often angular, shape because of a rigid cell wallCell is fl exible and more likely to be a rounded shape . 3. 6 Outline 2 roles of extracellular components (3). †¢The plant cell wall gives the cell a lot of strength and prevents it from bursting under high pressure as it is made up of cellulose arranged in groups called microfibrils. It gives the cell its shape, prevents excessive water up take by osmosis and is the reason why the whole plant can hold itself up against gravity. Prevents entry of pathogens. Allows turgor pressure/ high pressure to develop inside the cell. The animal cell contains glycoproteins in their extracellular matrix (ECM) which are involved in the support, movement and adhesion of the cell. Cell to cell interaction, strengthens plasma membrane, allows attachment between adjacent cells, directs stem cells to differentiate 2. 4. 1 Draw and label a diagram to show the structure of membranes (1). 2. 4. 2 Explain how the hydrophilic and hydrophobic properties of phospholipids help to maintain the structure of cell membranes (3). One area of membrane is water soluble and polar and is hydrophilic †¢The other area is n’t water soluble and is non polar- hydrophobic †¢These hydrophobic and hydrophilic regions cause phospholipids to always align as a bilayer if there is water present and there is a large number of phospholipid molecules †¢Membrane is flexible since fatty acid tail do not strongly attract one another †¢What maintains the overall structure of membrane is the tendency water has to form hydrogen bonds †¢In hydrophobic region (fatty acid tails) in animal cells these are cholesterol molecules- determine membrane fluidity (changes temp) †¢Proteins are embedded in fluid matrix of phospholipid bilayer (mosaic effect) †¢Integral proteins have both hydrophobic and hydrophilic regions in the same protein †¢Hydrophobic region (mid section of phospholipid membrane) holds protein in place †¢Hydrophilic region is exposed to water solutions on either side of membrane †¢Peripheral proteins do not protrude into the middle hydrophobic region but remain bound to the surface of the membrane 2. 4. 3 List the functions of membrane proteins (1). †¢Hormone binding sites- have specific shapes that fit shape of specific hormone †¢Enzymatic action- catalyze chemical reactions †¢Cell adhesion- proteins hook together to form connections †¢Cell to cell communication- provide identification †¢Channels for passive transport- high to low concentration †¢Pumps for active transport- proteins shuttle a substance from one side of membrane to another by changing shape; ATP 2. 4. 4 Define osmosis and diffusion (1). †¢Diffusion is the passive movement of particles from a region of high concentration to a region of low concentration. Osmosis is the passive movement of water molecules, across a partially permeable membrane, from a region of lower solute concentration to a region of higher solute concentration (hypo-osmotic solution to hyperosmotic solution). †¢Facilitated diffusion- involves a membrane with specific carrier proteins that are capable of combining with the substance to and its movement 2. 4. 5 Explain passive transport across membranes by simple diffusion and facilitated diffusion (3). †¢Simple diffusion- substances other than water move between phospholipids molecules or through proteins which possess channels †¢Facilitated diffusion- nonchannel protein carriers change shape to allow movement of substances other than water. No NRG. Polar molecules need help. †¢Substances that move passively across membrane are influenced by size and shape †¢Small substances and nonpolar move with ease; large, polar, or both do not †¢Channel proteins- create a hydrophilic pore in membrane through which small changed particles (ions) can diffuse into cell †¢Transport proteins- help move substances (glucose) into cell. Substrate binds to protein which carries molecules across membrane and releases it inside cell 2. 4. 6 Explain the role of protein pumps and ATP in active transport across membranes (3). †¢Active transport involves the movement of substances through the membrane using NRG from ATP. The advantage of active transport is that substances can be moved against the gradient, meaning from low to high concentration †¢This is possible because the cell membrane has protein pumps embedded it which are used in active transport to move substances using ATP †¢Each protein pump only transports certain substances so the cell can control what comes in and goes out †¢Transport or carrier proteins †¢Ex: Na +/ K + pump. Sodium moved out of cell, potassium moved in (important for nerve cells) 2. 4. 7 Explain how vesicles are used to transport materials within a cell between the rough ER, Golgi apparatus, and plasma membrane (3). †¢Materials are transmitted between rough ER, Golgi app, and plasma membrane †¢Nucleus contains chromosomes that contain genes for coding proteins. RNA passes from nucleus to cytoplasm †¢Rough ER contains ribosomes which make proteins intended for export †¢Protein goes into lumen of Golgi app for processing before it leaves through the cell surface membrane by exocytosis 2. 4. 8 Describe how the fluidity of the membrane allows it to change shape, break and reform during endocytosis and exocytosis (2). †¢The phospholipids in the cell membrane are not solid but are in a fluid state allowing the membrane to change its shape and also vesicles to fuse with it. †¢This means substances can enter the cell via endocytosis and exit the cell via exocytosis. The membrane then returns to its original state. †¢In exocytosis the vesicles fuse with the membrane expelling their content outside the cell. The membrane then goes back to its original state. Endocytosis is a similar process which involves the pulling of the plasma membrane inward so that a vesicle is pinched off it and then this vesicle can carry its content anywhere in the cell. †¢Cell takes up substance by surrounding it with membrane, ATP †¢2 types: †¢pinocytosis (substance is liquid) †¢phagocytosis (substance is solid) †¢endocytosis and exocytosis- active transport that requires ATP; common in unicellular organisms Summary of processes: ATP requiredConcentration gradient Diffusion NoDown (high to low) Facilitated diffusionNoDown OsmosisNoDown Active transport with carrier proteinsYesAgainst is possible EndocytosisYesAgainst is possible 2. 5 Cell Division 2. 5. Outline the stages in the cell cycle, including interphase (G1, S, G2), mitosis, and cytokinesis (2). †¢The first stage of cell division is interphase which is divided into 3 phases; G1, S and G2. The cell cycle starts with G1 (Gap phase 1) during which the cell grows larger. This is followed by phase S (synthesis) during which the DNA is replicated. Finally, G2 (gap phase 2) is the second growth phase in which organelles increase in number, cell grows and preps for mitosis, DNA begins to condense form chromatin to chromosomes and microtubules begin to form. †¢? The fourth stage is mitosis, which is divided into prophase, metaphase, anaphase and telophase. During mitosis the spindle fibers attach to the chromosomes and pull sister chromatids apart, providing the same genetic material to each of these locations. This stage separates the two daughter genomes. †¢Finally, cytokinesis is the last stage during which the cytoplasm divides to create two daughter cells. In animal cells the cell is pinched in two to form a cleavage furrow while plant cells form a plate between the dividing cells. 2. 5. 2 State that tumors (cancer) are the result of uncontrolled cell division and that these can occur in any organ or tissue (1). †¢Proto-oncogenes are genes that produce proteins, which stimulate growth (cell division). If mutation occurs, a tumor will form. Mutations: radiation, viruses, chemicals that are carcinogenic, EM radiation 2. 5. 3 States that interphase is an active period in the life of a cell when many metabolic reactions occur, including protein synthesis, DNA replication, and an increase in the # of mitochondria and/or chloroplasts (1). 2. 5. 4 Describe the events that occur in the 4 phases of mitosis (2). †¢During prophase, chromatin becomes chromosomes, nuclear envelope disintegrates, the spindle microtubules begin to form, centrosomes move toward opposite poles of cell due to lengthening microtubules. Each chromosome consists of 2 identical sister chromatids held together by a centromere. During metaphase, the chromatids move to the equator and the spindle microtubules from each pole attach to each centromere on opposite sides. †¢During anaphase, the spindle microtubules pull the sister chromatids apart splitting the centromeres. This splits the sister chromatids into chromosomes. Each identical chromosome is pulled to opposite poles. Chromatids of each duplicated chromosome separate and bec ome unduplicated chromosome †¢During telophase, the spindle microtubules break down and the chromosomes uncoil and so are no longer individually visible. Also the nuclear membrane reforms. Chromosomes become chromatin (shapeless). Centrioles replicate in animal cells. The cell then divides by cytokinesis to form two daughter cells with identical genetic nuclei. 2. 5. Explain how mitosis produces 2 identical nuclei (3). †¢During prophase, the chromosomes become visible. The nuclear envelope disintegrates and the spindle microtubules grow and extend from each pole to the equator. †¢At metaphase the chromatids move to the equator. The sister chromatids are two DNA molecules formed by DNA replication and are therefore identical. †¢These sister chromatids are then separated in anaphase as the spindle microtubules attaches to centromere and pulls the sister chromatids to opposite poles. As the sister chromatids separate they are called chromosomes. This means that each pole has the same chromosomes (same genetic material). Finally the microtubules break down, the chromosomes uncoil and the nuclear membrane reforms. The cell then divides into two daughter cells with genetically identical nuclei. †¢4 chromosomes in parent cell = 4 chromosomes in each daughter cell †¢duplicated chromosome with 2 strands connected by centromere and chromosome is 1 strand 2. 5. 6 State that growth, embryonic development, tissue repair, and asexual reproduction involve mitosis (1). †¢Growth- production of similar cells †¢Embryonic development- allows zygote to grow into multicellular organism †¢Tissue repair- wounds need identical replacement cells †¢Asexual reproduction- allows for a rapid and sig nificant increase in number of individuals How to cite An Outline of the Cell Theory, Papers

Saturday, December 7, 2019

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